
What is ibuprofen antipyretic? Ibuprofen’s antipyretic properties make it one of the most popular drugs for the treatment of fever. To understand how ibuprofen works as an antipyretic, let us dig deeper into its mechanism and effects on the body.
What Is Ibuprofen Antipyretic?
A 2004 study in the journal Pharmacology & Therapeutics found that ibuprofen was more effective than acetaminophen at reducing fever in children aged 6 months to 12 years with acute respiratory tract infections. It reduced their fever quicker, and was better at maintaining the lower temperature over time.
Overall, this study demonstrated that ibuprofen is an effective antipyretic agent for children with fever due to acute respiratory tract infection.
It is important for parents and caregivers to understand the differences between these two medications so they can make an informed decision about which one is best suited for their child’s needs.
Additionally, it is important to follow the dosage instructions provided by your healthcare provider when administering either medication as incorrect dosing can lead to adverse
PharmGKB summary: Ibuprofen Pathways

PharmGKB is a comprehensive online resource for pharmacogenetics and pharmacogenomics. It provides information about the genetic basis of drug response, including pathways related to ibuprofen.
Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) used to treat pain, fever, and inflammation. PharmGKB’s ibuprofen pathways provide an overview of the molecular mechanisms by which ibuprofen works in the body.
The pathways include information on how ibuprofen is metabolized in the body, its effects on various enzymes and proteins involved in inflammation, and its interactions with other drugs.
PharmGKB also provides data on genetic variants that may affect how individuals respond to ibuprofen. This includes information on gene polymorphisms that can influence the metabolism of ibuprofen or its effectiveness as a treatment for certain conditions.
By providing this information, PharmGKB helps healthcare professionals make informed decisions about prescribing medications based on individual patient characteristics.
The Antipyretic Effect of Ibuprofen and Acetaminophen in Children
The antipyretic effect of ibuprofen and acetaminophen in children has been studied extensively. Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) that is commonly used to reduce fever in children.
Acetaminophen is an analgesic and antipyretic medication that is also commonly used to reduce fever in children. Both medications have been found to be effective at reducing fever, but there are some differences between the two drugs.
Ibuprofen is more effective than acetaminophen at reducing fever, but it may cause gastrointestinal side effects and should not be given to children under 6 months old due to the risk of Reye’s Syndrome. Acetaminophen does not typically cause these side effects, and can be safely administered to infants as young as 2 months old.
Side effects of ibuprofen
Less common side effects of ibuprofen include ringing in the ears (tinnitus), blurred vision, confusion or depression, difficulty breathing or swallowing, swelling of the face or throat, hives or itching skin rashes, and chest pain.
If you experience any of these symptoms while taking ibuprofen it is important to contact your doctor immediately. It is also important to take the lowest possible dose for the shortest possible time needed to control your symptoms and always follow the instructions on the patient information leaflet that comes with your medicine.
Conclusion
Ibuprofen is an effective antipyretic drug for reducing fever in children aged 6 months to 12 years due to acute respiratory tract infections. It works by targeting certain enzymes and proteins involved in inflammation, and its effectiveness can be affected by gene polymorphisms.
Both ibuprofen and acetaminophen are effective at reducing fever, but ibuprofen may have side-effects such as ringing in the ears or hives. It is important to take it correctly and contact a doctor if any unexpected symptoms occur.
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